I reached a sad point in my Skyrim game that lead my game to crash every time I tried to save after awhile. It happened in one of my castle mods, then I backtracked to an earlier save and had issues again when trying to leave or save within the Soul Cairn.
With guidance of my friends I installed Mod Organizer and went through a clean reinstall of my mods. My goal was to get everything nice and neat, then create a new character. But I loaded my saves and the crashing was gone. So now I’m not so sure… I think I’ll just ride it out until I have problems again. So far I spent a good few hours running around the land doing quests and going about my business. So for now it seems my adventures haven’t been brought to a screeching halt.